Effect of the Photocatalyst under Visible Light Irradiation in SARS-CoV-2 Stability on an Abiotic Surface

There is a worldwide attempt to develop prevention strategies against SARS-CoV-2 transmission. Here we examined the effectiveness of tungsten trioxide (WO3)-based visible light-responsive photocatalyst on inactivation under different temperatures and exposure durations. The viral titer photocatalyst-coated glass slides decreased from 5.93 ± 0.38 logTCID50 /mL 3.05 ±. 25 logTCID50/mL after 3,000 lux light irradiation for 6h at 20℃. On other hand, lighting without photocatalyst, or photocatalyst-coat retained stability. Immunoblotting electron microscopic analyses showed reduced amounts spike protein surface treatment. Our data suggest possible implication decontamination in indoor environments, thereby preventing indirect spread.